Ecstasy

WARNING : “Wild” taking of MDMA (ecstasy) outside of therapeutic supervision can cause death. The testimony of Louis' father is a very clear warning given to any user.

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MDMA, or 3,4-methylenedioxy-N-methylamphetamine, was first synthesized in 1912 by German chemist Anton Köllisch . However, it wasn't until decades later, in the 1970s, that MDMA began to be used recreationally. Originally developed for pharmaceutical applications, MDMA quickly became popular in party circles and was associated with electronic music and rave culture.

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The effects of ecstasy are varied and can include feelings of euphoria, increased empathy, emotional openness, and physical stimulation. MDMA works by increasing the release of serotonin, dopamine and norepinephrine in the brain, creating a feeling of well-being and connection with others. However, it is important to note that MDMA consumption can also lead to health risks, such as dehydration, hyperthermia, and cardiovascular complications.

There are multiple current modes of ecstasy consumption:

·       Tablets or capsules: MDMA is often sold in tablet or capsule form. These forms can contain varying doses of the substance, and the quality can vary greatly.

·       Crystals or powder: MDMA can also be present in crystals or powder form. In this case, it is often inhaled (snorted) or dissolved in a liquid and consumed orally.

·       Combined with other substances: Unfortunately, in some cases, MDMA sold on the street can be contaminated or mixed with other substances, increasing health risks.

·       Risk Reduction Mode: Some users practice risk reduction strategies, such as taking smaller doses, spacing out doses, and monitoring hydration to minimize the risks associated with MDMA use.

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Its therapeutic use has attracted renewed interest in recent years. Research primarily focuses on its potential in treating specific mental health disorders. Here are some areas where MDMA is currently being studied for therapeutic purposes:

·       Post-traumatic stress disorder (PTSD): MDMA is being studied for its potential in treating PTSD, particularly in individuals for whom other treatments have not been successful. MDMA-assisted psychotherapy sessions can help patients revisit traumatic experiences and process them in a more constructive way.

·       Anxiety related to terminal illness: MDMA is being explored for use in terminally ill patients facing significant anxiety related to their health condition. MDMA-assisted sessions can facilitate emotional expression and help alleviate psychological distress.

·       Autism: Preliminary studies are examining the use of MDMA in the treatment of autism, focusing on improving social skills and reducing anxiety in people with this neurodevelopmental disorder .

·       Therapeutic relationship: MDMA is also being studied for its potential to improve the therapeutic relationship. It could facilitate open and honest communication between patient and therapist, thereby promoting deeper exploration of underlying issues.

·       It is important to note that these studies are still at an early stage and further research is needed to evaluate the effectiveness and safety of the therapeutic use of MDMA. Research protocols often use controlled doses of MDMA under the supervision of mental health professionals.

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Note that unlike other psychedelic molecules, there is little specific research on the microdosing of MDMA. Most studies focus on higher doses in specific therapeutic settings. The lack of data makes it difficult to assess the potential benefits and risks associated with microdosing MDMA.